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MK-677 (also known as Ibutamoren or Nutrobal) acts as a potent, orally active growth hormone secretagogue. By mimicking the growth hormone stimulating action of the endogenous hormone ghrelin, MK677 is designed to stimulate the pituitary gland to increase release of and produced sustained increases in plasma levels of several hormones including growth hormone and insulin-like growth factor 1 (IGF-1), with little to no increase in cortisol. As a potent orally administered growth hormone releasing compound, MK-677 provides many of the benefits of injectable GH releasing peptides, such as Ipamorelin or GHRP6, without the need for injections.
Originally developed with aims to combat conditions such as muscle wasting, obesity, and osteoporosis, studies have shown it to increase bone mass and bone mineral density, alter the metabolism of body fat, as well as improve sleep quality by increasing REM sleep.
Orally active, this bioavailable compound has a half-life of 24 hours, so it does not need to be taken according to a specific timing schedule, meaning that a single once a day dosing is sufficient. MK-677 increases the frequency of the body’s low amplitude natural growth hormone pulses, not the amplitude of individual pulses. This means that MK-677 works synergistically with the body, without pushing it past its natural set point.
Acting on the ghrelin receptor to stimulate growth hormone release, MK-677 can have ghrelin-like properties and individuals may notice a very slight increase in appetite when beginning administration.
Please note, as this is a prescription item, one of our doctors will review your profile and approve your order if appropriate. A prescription will only be issued in accordance to the prescribing guidelines, and for use that strictly complies to the doctor’s directions and dosage. This script will be forwarded to our dispensary team, and placed in our secure, internal records.